ATB

First dose: full dose, then according to kidneys

- ATB -	- Dose -
Meropenem	2 g first dose, then 1–2 g VI Q8h

- Site -	ATB
Urosepsis	ESBL coverage: meropenem (works for Enterococcus also)
Pneumonia

- Species -
MRSA

- Severity -


- Scared (risk tolerance) -



- Special cases -
Splenectomy
Neutropenia

Hydrocortisone 50 mg IV Q6

Time dependent	fT > MIC	frequent/prolonged/continuous infusion	beta-lactams (fT > MIC 40–100 %), lincosamides (clindamycin, lincomycin)
(Peak) Concentration dependent	Cmax > MIC	high doses with extended-interval	aminoglycosides, fluorochinolones
Concentration dependent with time-dependence (mixed)	AUC/MIC	vancomycin, cotrimoxazol, linezolid, macrolides, tetracyclines, daptomycin, polymyxins

Ampicilin/Sulbactam 1.5 g ad 100 ml F1/1 i.v. na 30 min. 12-18-24-06 h. den 1
Ampicilin/Sulbactam 3 g ad 100 ml F1/1 i.v. na 30 min. 12-18-24-06 h. den 1
Ampicilin/Sulbactam 3 g ad 50 ml F1/1 i.v. kontinuálně rychlostí 8.3 ml/h den 1

ATB I.V.:

AMI x. Amikacin 1g inf 100ml na 60' F1/1 i.v. á 24h (hladinu nabrat před od D3, podat, následně upravit interval)
AUG x. Augmentin 1,2g inj.ad 100ml F1/1 i.v. na 30' á 8h 16 - 24 - 08
AMPI x. Ampicilin 2g inj. ad 100ml F1/1 i.v. na 30' á 6h 12-18 – 24 - 06
AVRA x. Avrazor 500mg amp. ad 100ml F1/1 i.v. na 60' á 12h 20 - 08
AVE x. Avelox 400mg/250ml inf. na 60´ i.v. á 24h 12
BISE x. Biseptol 960mg inj. ad 100ml F1/1 na 60´ á 12h 18 - 06
CEFTR x Ceftriaxon/Lendacin inj.1g ad 100ml F1/1 iv na 60‘ á 6h
CIPRI x. Ciprinol 400mg inf.i.v. na 30' á 12h 12 - 24 (200mg i.v. á 8h)
DALA x Dalacin C 600 mg inj. ad 250ml F1/1 na 30' iv á 6h 12-18-24-06
NELO x. Nelorem 600mg inj. ad 100ml F1/1 na 30' i.v. á 8h 14 - 22 - 06
COLI IV x. Colomycin 2/3 MU inj ad 100ml F1/1 na 30' i.v. á 8h 14 - 22 - 06
EFLO x. Efloran / Metronidazol 500mg inf.i.v.na 60' á 8h 14 - 22 - 06
ERAM x. Eramfat 600 mg inj.ad 500ml F1/1 na 3-4h iv á 24h
GENT x. Genta 400mg inj. ad 250ml F1/1 na 60' á 24h (hladinu před od D3)
KLAC x. Klacid 500mg inj. ad 100ml F1/1 i.v. na 30' á 12h
MAXI x. Maxipine 2g inj. ad 100ml F1/1 iv na 30' á 12h
MERO x. Meronem 2g bolus + 1g plv sol. ad 50ml F1/1 kont. R= 8,4ml/h
INV x Invanz 1g inj. ad 100ml F1/1 na 30´ i.v. á 24h
FURA x Nitrofurantion 100 mg tbl PO x NGS á 8 h
OFLO x Ofloxin 400 mg inj. ad 100ml F1/1 na 30' iv á 12h
OXA x. Oxacilin 3(2)g inj. ad 100ml F1/1 i.v. na 30' á 4h 10-14-18-22-02–06
SYNE x. Synercid 500mg ad 100ml G5% i.v. na 60' á 8h 14-22-06
TARGO x Targocid 400mg iv á 24h (první 3 dávky á 12h)
TAVA x Tavanic 500 mg iv á 12h
TAZO x. Piperacilin/tazobactam - Tazocin 4,5g amp. ad 250ml F1/1 na 3h i.v. á 6h 12-18-24-06
Tazocin 4,5g amp. + F1/1ad 50ml kont. R= 12,5ml/h 12-18-24-06
TIE x. Tienam 1g inj./ad 250ml F1/1 i.v. na 3h á 6h 12-18-24-06
TYGA x Tygacil 100mg plv.sol ad 100 F1/1 i.v. na 30' á 12h 22-10
UNA x Unasyn 1,5g plv sol.ad 100ml F1/1 i.v. na 30' á 6h 12-18-24-06
x. Unasyn 3g plv.sol. v 100ml F1/1 i.v. na 30min á 6h 12-18-24-06
UNA CONT x. Unasyn 3g plv.sol. + F1/1 ad 50ml R= 8,3ml/h
VANKO x. Edicin 0,5g amp. bolus i.v. dále 2g + F1/1 ad 50ml R=2ml/h
ZITRO x. Zitroxin 500mg ad 250ml F1/1 na 60‘ á 24h
ZYVO x. Zyvoxid 600mg/300ml inf. i.v. na 60' á 12h 12-24

Enterálně ATB:

VANKO EN x. Edicin 250mg inj v 20 ml F1/1 do NGS á 6 h 12 - 18 - 24 - 06
ENTI ENx. Entizol 250mg tbl.á 6 hod. 12 - 18 - 24 - 6

Antivirotika:

CYME x. Cymevene 500mg inj. ad 100ml F1/1 na 30' i.v. á 24h 10
FOSCA x. Foscarnet 210ml inf. kapat 2 h 8-20
HERPE x. Herpesin 500mg inj. ad 100ml F1/1 na 60' i.v. á 8h 14 – 22 - 06
RELEN x Relenza 2tbl/5ml F 1/1 á 12 h NEBULIZACÍ 10 - 22

Antimykotika IV:

MYCO x. Mycomax/ Fluconazol 400mng/200ml inf. na 60ˇi.v. á 8h 14 - 22 - 06
AMFOB IV x. Fungisone 100mg inj ad 250ml 5%G na 3h á 24h 08
AMFO IV x. Amphocil 400mg inj.ad 500ml G5% na 3h i.v. á 24h 10
ABLA x. Abelcet 350mg inj. ad 250ml G5%, na 3h i.v. á 24 h 12
CANCI x. Cancidas 50mg inj.(70mg 1.den) ad 100ml F1/1 na 60' á 24h 12
ECAL x. Ecalta 100mg inj.(200mg 1.dávka) ad 100ml F1/1 na 60' á 24h 12
VFE x. V-fend 200mg inj. ad 100ml F1/1 (400mg 1.den) i.v. na na 30' á 12h 10 – 22
MYCA Mycamine 100mg inj. ad 250ml F1/1 na na 60' iv á 24 h

Antimykotika NEBUL:

AMFOB NEB x. Fungisone 10mg inj. v 2ml aqua á 8h NEBULIZACÍ 16-24-08
COLO NEB x. Colomycin 1 MU inj. v 5ml F1/1 á 8h NEBULIZACÍ 14-22-06

ATB intranasálně:

Fungizone nosní sprej: 7 stisků do každé nostrilly 12-18-24-06
příprava: naředit 50mg do 5ml Aqua, naplnit do lahvičky
od nosního spreje Vincentka nosní sprej (1ml=10mg=14 stisků)

ATB PMK: výplachy á 6h - instilace, zavřít na 5h, 1h ponechat volně vytékat

AMFOB MM x. Fungisone 10mg inj.ad 20ml F1/1 á 12h 18 - 06
COLI MM x. Colomycin 0,5MU inj. ad 20ml F1/1 á 12h 24 – 12
VANC MM Vancocin 250mg inj. ad 20ml F1/1 instilovat do MOČ.MĚCHÝŘ á 6h 12-18-24-06 na 1h zaštípnout

Antibiotics

Dose

Choosing ATBx

PK Groups

Dose